Professor Charles Francis Xavier, who has the mutant ability to read minds, searches for new mutants to train them how to use their powers for good and to prevent the mutants from harming themselves and others at his School for Gifted Youngsters. His opposition, Magneto Master of Magnetism, is doing the same thing, but for evil purposes. He has made Mystique who is a shape-shifter, a principle of his high school to gather evil mutants to prepare them for war against non-mutants. The most interesting plot of the story is that all the heroes and villains attend the same high school. The classic battle of good vs. evil has begun again.
Adult Swim宣布《瑞克和莫蒂》推出一部衍生剧:日本动画风的《Rick and Morty: The Anime》,佐野隆史(《神之塔》)执导,已获预订整季10集,被描述为一个关于“这个很棒的家庭”的新故事,独立于主线之外,但会包括《瑞克和莫蒂》的主题和事件。
佐野隆史此前打造过两部《瑞克和莫蒂》的衍生短片:《瑞克和莫蒂对抗种族灭绝者》和《瑞克和莫蒂外传姐姐遇见上帝》。